Diversity, Inclusion and Equality (In T1D Research) I think it is important that we all support the Black Lives Matter movement in whatever we do. Interestingly, one of the lead UK study authors, Dr. Roy Taylor, says this may indicate a new focus for type 2 diabetes management and messaging that the medical community should embrace: weight loss is a way to better handle the rising T2D epidemic globally. Insulin maker Eli Lilly and Swiss pump company Ypsomed are creating a new automated system for people with diabetes. The results of this study will contribute to tailored therapies for patients with type 1 diabetes. ProfessorPenn State UniversityUniversity Park, PA. Purpose:Dr. Ozbolat previously demonstrated the micro-vascularization of engineered pancreatic islets in fibrin constructs under static conditions, where capillaries sprouted into the constructs facilitating intravascularization in engineered islets as well as capillary network around the islets. It’s also notable that earlier this year the ADA unveiled updated diabetes and pregnancy guidelines outlining everything from BG and blood pressure targets, to medications to avoid during pregnancy, to lactation management and postpartum care. Still, they insist that taking vitamin D capsules is a good choice for anyone with diabetes: “These findings do not change the need for all individuals to meet the vitamin D requirements set out by the Institute of Medicine. She discussed the evidence from five clinical trials examining low-carb eating and a systematic review of health outcomes. The current research, the authors note in their study paper, was made possible thanks, in part, to financial support from the research charity Diabetes UK. At the Forefront of Diabetes Research The U.S. government spends more than $1 billion a year on diabetes research. Future research may involve taking these cavefish into higher-up waters to gauge the impact, and exploring how that knowledge might translate into human-based interventions. DiabetesMine reviews Tandem Diabetes exciting new Control-IQ system that partially automates insulin delivery. The poster hall alone displayed a whopping 2,000+ research posters. Purpose:Roux-en-Y gastric bypass (RYGB) surgery is regarded as the gold standard treatment of obesity and obesity-related type 2 diabetes. Dr. Shornick proposes an innovative three-dimensional wound dressing containing New Zealand manuka honey which has special properties. Researcher:Douglas Sobel, MDProfessor of Pediatrics, Chief Pediatric EndocrinologyGeorgetown UniversityWashingotn, DC. At the Diabetes Research Institute and Foundation, the vision is a world without diabetes. But the, We found that among people with prediabetes and sufficient vitamin D level, vitamin D supplementation at 4,000 units per day did not significantly reduce the risk of diabetes.”, Innovative Simple Intervention to Improve Adherence, New Diabetes Research Presented at #ADA2019, DiRECT (Diabetes Remission Clinical Trial), Pittsburgh Epidemiology of Diabetes Complications (EDC) study, The Emotional Toll of Diabetes Complications, a study on insulin resistance in dark-dwelling cavefish, I Tried It: Tandem’s New Control-IQ Automated Diabetes Technology. While many organizations and clinicians are embracing TIR these days, we have a long way to go in making it an established measure that researchers, industry and regulators accept into their processes. The researchers hope that this will lead to an increased number of B-cells that function normally so that the blood sugar levels can be kept under control. The routine: Upon waking up in the morning, teens fed the fish one pellet and also checked and logged their own glucose levels; the same bedtime routine, and once a week they changed the fishtank water and also reviewed their BG logs with a healthcare provider. Though diabetes has no known cure right now, you should be aware of the recent medical advances and discoveries as researchers work on finding a cure and improving treatments. Every $1 the ADA invests in diabetes research leads to $12.47 in additional research funding. Current therapies would be more effective when used in patients at high risk for developing type 2 diabetes before the metabolic imbalances set in. Of course there were many sessions focused on nutrition and food-related topics, including numerous mentions of the ADA’s Nutrition Consensus Report released earlier this year. of Neurology, Anatomy and NeurobiologyVice Chair for Research, Dept. Pregnancy-associated Protein Linked to Gestational Diabetes … Purpose:Islet transplantation is a promising approach to cure type 1 diabetes and some people with type 2 diabetes, but current treatment requires high dose toxic systemic immunotherapy to prevent rejection. Cognitive function is decreased and the incidence of stroke is increased by diabetes. There is a lot of research on diabetes happening all around the world and the latest include: March 19, 2015: Research to Identify and Correctly Treat Rare Forms of Diabetes Some very rare forms of diabetes are caused by single gene mutations. As a hallmark feature, obesity is accompanied with chronic inflammation leading to potential cell damage and organ dysfunction. The 2017 Millennium Award – Type 2 was awarded to Dr Seth Masters of The Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne. Yet, as Researcher:Jeffery S. Tessem, Ph.D., Assistant Professor of Nutrition ScienceBrigham Young UniversityProvo, UT. The study aims to develop an orally administered gut-coating formulation that provides a transient barrier to nutrient contact with the proximal intestinal mucosa, thus recreating an important aspect of the surgical procedure non-invasively. Typically, patients will need to wait months due to paperwork, insurance, and logistical issues before they can utilize these technologies. The translation of this research into practice has led to reduc-tions in chronic complications and mor-tality in people with diabetes (6). Dr Master’s research focuses on the role of NLRP1 and IL-18 in type 2 diabetes. Researcher:Laurie P. Shornick, PhD Associate Professor of BiologySaint Louis UniversitySt. Purpose:The rise of obese population in the U.S. indicates more people with type 2 diabetes in the future, which can be attributed to genetic and nutritional factors. In what’s dubbed the DiRECT (Diabetes Remission Clinical Trial) study, researchers also found that in early type 2, insulin-producing beta cells are not damaged and “irreversibly lost” as previously thought. These studies are expected to identify new factors in control of insulin signaling pathway which may serve as useful targets for drug development. Type 2 diabetes (T2D) However, during diabetes there is impaired vasodilation, and thus impaired neurovascular coupling. This study will determine how effective RA and RA-amide are in ameliorating diabetes and related neurodegeneration in a diabetic animal model. Whilemostofthoseindividualshavetype 2diabetes,nearly1millionAmericanshave type 1 diabetes. That was apparent in some of the smaller exhibitors especially, such as a booth selling customized lab coats for HCPs. PDF | Diabetes is one of the most common diseases worldwide. Current Research into Cures for Type-1 Diabetes News and updates on potential cures for type-1 diabetes, that are in human (or clinical) trials. View Study. Contact Us Phronesis, LLC 5 Great Valley Pkwy, STE 235, Malvern PA 19355, USA E-mail: diabetes@phronesisonline.com Tel: +1-302-469-7080 The proposed investigation will test the hypothesis and examine the efficacy of immunotherapy on both type-1 and type-2 diabetes induced kidney failure. Diabetes Educ. Naturally, the researchers hypothesized that more “destructive communication” (e.g., criticism) would be associated with poorer outcomes (i.e., lower levels of relationship satisfaction and higher levels of depressive symptoms), and vice-versa. 1(3). We do this by funding research towards the prevention, management or cure for diabetes. Current Research. If this project is successful, 50-60% of T1D patients who have specific high risk gene may benefit from this therapeutic modality. Current Research on Diabetes. Research, including the Diabetes Prevention Program Outcome Study (DPPOS), that evaluates the success of diabetes interventions and strategies. The dressing will provide a structure for cells to migrate into the wound, and the honey will provide anti-bacterial protection and will promote the formation of new tissue and blood vessels. Improved glycemic control is associated with amelioration of diabetic neuropathy but there is no treatment that prevents neuropathy developing or progressing. Current Research in Clinical Diabetes and Obesity is a peer-reviewed open access journal which publishes emerging concepts and disseminates the ongoing research in multidisciplinary fields of Diabetes and Obesity. Although these phenotypes are observed, these compounds have limited intestinal absorbance and are not observed in circulation. Whether micronutrients such as Vitamin A (VA) play a role in type 2 diabetes development is still an open question. Researchers found those fish have higher fasting glucose levels, which could have implications for human studies on ways to improve insulin resistance. Learn more See ADA research funds at work. A research study to help improve treatment of type 2 diabetes, by learning how individuals respond to different blood sugar-lowering drugs. Find out more. Investments in type 1 diabetes research The CDC estimates that nearly 1.6 million Americans have it, including about 187,000 children and adolescents. We’d like to share some of the topics that most caught our eye: One of the most-discussed studies presented at this year’s conference was from the ongoing nationwide study TrialNET, showing that in those who are at “high-risk” for type 1 diabetes (i.e. When honey warms to body temperature, it may also leak out of the wound. Medical Disclaimer - The content on this website is provided for general information only and should not be relied upon as a substitute for any professional medical advice or treatment. Type 2 diabetes (T2D) One of the quirkiest presentations came from Dr. Olga Gupta of the University of Texas Southwestern Medical Center, who did a study showing that caring for pet fish can help adolescents with higher A1Cs who weren’t previously managing their diabetes as well as they should be. Detailed understanding of how the insulin signaling pathway is regulated and how this pathway is disrupted during the progression of type 2 diabetes should provide a better way to reduce insulin resistance. However, very little vitamin D is found in food, and your body’s ability to make vitamin D from sunlight depends on many factors, including your exposure to the sun, where you live, the time of year, and the time of day. For close to 70 years, the American Diabetes Association (ADA) has dedicated its resources to research, educate, legislate, and fight for progress and against discrimination. At the Forefront of Diabetes Research The U.S. government spends more than $1 billion a year on diabetes research. Despite these correlations, there are no studies directed towards understanding the role of industrial chemical exposure in T1D development. People get vitamin D from food and sunlight. Specifically, increased brain omega-3 PUFA increases the production of pro-resolving lipid mediators which decrease inflammation. Purpose:Insulin plays an important role in maintaining normal blood glucose levels by activating a series of actions referred to as the insulin signaling pathway in insulin target tissues. In that “year in review” highlights session towards the end of the ADA conference, Dr. Daniel Drucker of Mt. As cases of the novel coronavirus began presenting and comorbidities like diabetes impacted patients at significantly higher rates, we knew that our work to find a cure was more important than ever. To achieve their goal to safely inhibit rejection of islet transplantation, they will explore an important potential local immunotherapy drug entanercept, fully determine the optimal doses for the drug enladed PLGA, and assess the proper doses to prevent toxicity to the transplanted insulin producing cells in diabetic mice in order to cure them of their diabetes without rejection of the new insulin producing cells. Meanwhile, the ADA is making an effort to better connect with the patient community through its recent rebranding effort. Over the last year, Dr. Sobel’s lab has made much progress to overcome major obstacles that have prevented this therapy. Therefore, understanding the underlying mechanisms responsible for obesity-associated chronic inflammation and the consequences on myocardial dysfunction is significant. The study included a whopping 2,423 participants from 22 locations across the US. Publications. It is a result of insulin resistance and loss of insulin secreting beta-cells. Five additional clinic trials with BCG/placebo to over 200 subjects are currently ongoing. They have synthesized a new PLGA-Microsphere system able to release three important drugs to prevent islet rejection over a very long period of time, characterized the physical properties of the microsphere system, and by doing this, have made headway to determine the optimal drug doses within the PLGA. Particularly in the case of chronic conditions such as diabetes, groundbreaking research can transform and save lives. It certainly is, and when that research is in the field of medicine, the impact on humankind can be immense. Diabetes and Diet Current Research. Type 1 diabetes develops when a person's immune system wipes out insulin-producing beta cells in the pancreas. Professor Curtis and his research team want to test a new drug that could slow or stop retinopathy earlier on in its development. One well-attended session was led by CDE and fellow T1D Patti Urbanski, addressing the benefits of a low-carb diet for adults with all types of diabetes (T1, T2, and Prediabetes). So naturally, last week’s 79th annual event – held in an unseasonably hot downtown San Francisco – featured updates on loads of new studies from around the country and world, now ready to be presented to medical peers. Current Research in Diabetes & Obesity Journal is an international peer reviewed Open Access journal of Juniper Publishers. Lilly and Ypsomed Developing New Automated Insulin Delivery System, Hot New Technology from Medtronic Diabetes, Around the Diabetes Online Community: November 2020, People of Color Speak Out on Diabetes Technology and Care, Everything You Should Know About Coronavirus and Diabetes, The Lowdown on Hypoglycemia (Dangerously Low Blood Sugars). Furthermore, obesity is associated with increased lipid accumulation in many tissues. And in the big wrap up session on science advancements in the past year, there was mention of a study on insulin resistance in dark-dwelling cavefish who live at the bottom of the ocean where nutrients are limited. We will test the ability of the humanized mAb1E7 to inhibit disease associated auto-reactive lymphocytes of T1D patients. current research on diabetes nutrition. Our research's impact. Diabetes can affect many parts of the body and is associated with serious complications, such as heart disease and stroke, blindness, kidney failure, and lower limb amputation. Purpose:As an emerging epidemic in the US and worldwide, obesity is associated with a constellation of metabolic disorders including insulin resistance, glucose intolerance, type 2 diabetes, hypertension and cardiovascular abnormalities. Dr. Liu discovered for the first time that hispidulin, a compound isolated from the herb Salvia plebaia, which is also abundant in oregano, acts in the gut to promote beta-cell function and ameliorates T2D, while sulforaphane, a small molecule derived from cruciferous vegetables, is a potent insulin sensitizer in the body of T2D mice. The researchers also hope to facilitate the development of T cells that can suppress the remaining disease-causing T cells. The principal investigator of this proposal has investigated the roles of VA in the regulation of sugar and fat metabolism since 2006. Investments in type 1 diabetes research The CDC estimates that nearly 1.6 million Americans have it, including about 187,000 children and adolescents. The goal of this study is to determine the role of omega-3 derived pro-resolving lipid mediators on inflammation in the brain of diabetic mice. One potential molecule link between these diseases is a molecule called amylin. The American Diabetes Association funds a productive research portfolio that offers significant progress and hope for improved outcomes for people with type 1 diabetes. Healthline Media does not provide medical advice, diagnosis, or treatment. However, they also need to determine if NR can prevent neuropathy in type 1 diabetes and if the effect can be sustained. Many in the D-Community have been arguing for years that beyond A1C, the three-month average glucose measure that is currently gold standard, Time-in-Range (TIR) possibly matters more. Recently published articles from Diabetes Research and Clinical Practice. What diabetes funding is available generally goes to established scientists. Oh, the complexity of human relationships! Current clinical research on type 2 diabetes and its prevention in youth. However, its invasive and non-reversible nature has limited its application to small patient subgroups. 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